Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a late‑onset fatal neurodegenerative disease affecting motor neurons characterized by progressive loss of the upper and lower motor neurons (LMNs) at the spinal or bulbar level with an incidence of about 1/100,000. The disease reflecting degeneration of motor neurons in the primary motor cortex, brainstem and spinal cord.

"Amyotrophy" refers to the atrophy of muscle fibers, and is a progressive wasting of muscle which are denervated as their corresponding anterior horn cells degenerate, leading to weakness of affected muscles and visible fasciculations.

"Lateral sclerosis" refers to the hardness of the anterior and lateral corticospinal tracts as motor neurons in these areas degenerate, where gliosis follows degeneration of the corticospinal tracts.

The feature of ALS was first described in 1869 by French neurologist Jean-Martin Charcot. The disease commonly known as Lou Gehrig’s disease became well known in the United States when baseball player Lou Gehrig was diagnosed with the disease in 1939.

Most ALS cases are sporadic, but about 5–10% of ALS is familial, with a Mendelian pattern of inheritance. Both sporadic and familial ALS (FALS) are associated with degeneration of cortical and spinal motor neurons.

Also known as Charcot disease, ALS is one of the five motor neuron disease (MNDs) that affect motor neurons, while the other four knowns as: Primary lateral sclerosis (PLS), progressive muscular atrophy (PMA), progressive bulbar palsy (PBP), and pseudobulbar palsy.
Amyotrophic Lateral Sclerosis

Bipolar disorder

Bipolar disorder or manic-depressive illness is one of the most common, severe and persistent mental illness. It is a chronic disease.

Bipolar disorder is characterized by periods of deep, prolonged and profound depression that alternates with periods of an excessively elevated or irritable mood known as mania

People who have bipolar disorder experience extreme changes in mood, energy, and behavior. They alternate, or switch, between two opposite emotions. Bi means ‘two’ and polar means ‘opposite’.

Their mood repeatedly alternates from extremely happy, or high, to sad and hopeless.

Most of the scientists agreed that the condition is linked to certain abnormalities in the brain. Bipolar disorder is considered a physiological condition and not simply a psychological illness.

There are four factors that make people vulnerable to bipolar disorder:
*Heredity genes
*Abnormal brain structure and function
*Environmental factors
*Psychological factors
Bipolar disorder

Fruit And Vegetable Juice Consumption May Reduce Risk Of Alzheimer's Disease

Various health functions of fruit and vegetable juice have been reported in recent years. Diets rich in fruits and vegetables were found to be protective against the risks of chronic diseases such as cardiovascular disease, arthritis, chronic inflammation and cancers.

Drinking fruit and vegetable juices frequently may also delay the onset of Alzheimer's disease, particularly among those who are at high risk for the disease

In August 2006 The American Journal of Medicine published a study concluding that drinking fruit and vegetable juice reduces the likelihood that person will develop Alzheimer’s disease.

The study shows that who drank and 8 ounce glass of the juice three or more times weekly were 76 percent less likely to develop Alzheimer’s disease than those who drank less than one serving.

Researchers believed that polyphenols a class of antioxidants in fruit and vegetables, seem to have a protective effect on the brain, reduce the likelihood of dementia and prevent the development Alzheimer’s disease.

Alzheimer’s has been linked to the accumulation in the brain of a harmful type of protein known as beta-amyloid. It was believed that the buildup of beta-amyloid protein in the brain is due to damage cause by free radicals.

Both fruit and vegetable juices contain a wide variety of nutrients that help to keep blood vessels in good working order and maintain healthy blood pressure levels.

Polyphenols have been identified on edible plants and have antioxidants properties as well as probable role in the prevention of Alzheimer’s disease with associate growth oxidative damage.
Fruit And Vegetable Juice Consumption May Reduce Risk Of Alzheimer's Disease