German-born American neurologist, Frederic Henry Lewey was the first who described eosinophilic inclusion bodies or Lewy bodies. The term Lewy bodies was first coined by Tretiakoff in his thesis at the University of Paris in 1919.
Lewy bodies are rounded, eosinophilic, intracytoplasmatic neuronal inclusions.
Lewy body dementia is an umbrella with Lewy bodies and Parkinson’s disease with dementia.
In all Lewy body disorders, tiny abnormal round structures called Lewy bodies develop in regions of the brain involved in thinking and or movement.
Lewy body dementia is a complicated disease to diagnose because may other symptoms can present that seem unrelated first.
*Shallow breathing problems and low voice projection
*Poorly in attention, learning and constructional praxis
*Temperature regulation, either too hot or too cold
*Digestion problems such as nausea or constipation
*Urinary, bowel and sexual problems.
*Any sudden, unexplained loss of consciousness
*Autonomic dysfunction
*Sleep issues
Most experts used the term Lewy body dementia (LBD) to refer to the histopathological disorder, but other diagnostic terms included diffuse LBD, cortical LBD, LB dementia, and the LB variant of Alzheimer’s disease.
Lewy body dementia (LBD)
