Neuronal dysfunction—such as epilepsy, multiple sclerosis and Parkinson’s disease—inflict great pain and suffering on patients and their families, and every year costs the U.S. economy billions of dollars.
Neuronal dysfunction refer to a large number of disorders that involve the structures and functions of the central nervous system (brain and spinal cord) and/or the peripheral nervous system (the motor and sensory nerves outside the brain and spinal cord.
They are defined as an inappropriate function of the peripheral or central nervous system due to impaired electrical impulses throughout the brain and/or nervous system that may present with heterogeneous symptoms according to the parts of the system involved in these pathologic processes. Approximately one-third of the affected individuals develop neurological symptoms before the age of 10 years.
The magnitude and burden of mental, neurological, and behavioral disorders is huge, affecting more than 450 million people globally. According to the Global Burden of Disease Report, 33 percent of years lived with disability and 13 percent of disability-adjusted life years (DALYs) are due to neurological and psychiatric disorders, which account for four out of the six leading causes of years lived with disability.
Neuronal dysfunction
