The combination may occur with other clival lesions, particularly tumors, although occasionally lesions within the lower brain stem or meninges may produce this clinical picture.
It consists of ophthalmoplegia and trigeminal neuralgia usually associated with paralysis of the tongue. The tumor is located in the nasopharynx extending intracranially.
Lesions within the hypoglossal canal are rare. Inflammatory, neoplastic or traumatic lesions in the region of the occipital condyle may cause isolated hypoglossal palsy and a characteristic pain pattern (occipital condyle syndrome); it is most often due to metastatic disease to the skull base.
Godtfredsen's syndrome
